Kyrgyz-Russian Slavic University was founded in 1993 by the Treaty of Friendship, Cooperation and Mutual Assistance between the Kyrgyz Republic and the Russian Federation (signed on 10.06.1992, Moscow, Russia), the Decree of the President of Kyrgyz Republic ( signed on 28.09.1992, Bishkek, Kyrgyz Republic) and the Agreement of Establishment and Activities of Kyrgyz-Russian Slavic University between the Government of the Kyrgyz Republic and the Government of the Russian Federation (09.09.1993), the Enactment of the Government of the Russian Federation (No.143, signed on 23.02.1994, Moscow), the decrees of the State Committee of the Russian Federation for Higher Education No. 326-128/1 (14.02.1994) and the Ministry of Education and Science of the Kyrgyz Republic.
Since its establishment, the university has been cooperating with the Yeltsin Foundation that remains a trusted partner up to the present day. The foundation has been providing financial support to the university such as grants for 50 best students, provision with modern learning equipments as well as financial support with the Internet access of the whole university. In addition, the Yeltsin Foundation has supported various schools and university based academic competitions of Russian Language, international research and practice conferences on maintaining positive integrated learning environment within the CIS countries.
In 2004 by the decree of the President of the Kyrgyz Republic, as an expression of appreciation and respect for enormous support and encouragement in founding the Kyrgyz-Russian Slavic University, the university was given a name of the First President of Russian Federation Boris Nikolayevich Yeltsin.